
Cellular aging
Cardiogen
Synthetic Ala-Glu-Asp-Arg tetrapeptide for cardiac tissue and gene-regulation research.
$59.99
/ 25mg vial · TDL-CARDIOGEN-25MG
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$59.99
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Same-day · by 2 pm CT
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Research profile
Cardiogen is a research peptide used in preclinical laboratory models involving cardiac tissue biology and peptide-mediated gene regulation.
What is it?
Cardiogen is a synthetic tetrapeptide (Ala-Glu-Asp-Arg) from the Khavinson class of short peptide bioregulators developed at the Saint Petersburg Institute of Bioregulation and Gerontology. It belongs to the same structural family as Epithalon and other short-chain bioregulators studied in Russian biogerontology literature.
The bioregulator model proposes that short peptide sequences of two to four amino acids can interact with specific regions of DNA in a tissue-selective manner, influencing transcription of genes involved in tissue maintenance and cellular homeostasis. In preclinical research, Cardiogen has been examined in the context of cardiomyocyte differentiation markers, extracellular matrix composition, and age-related change in cardiac gene expression.
Mechanism of Interest
- Peptide–DNA Interaction — Studied under the Khavinson bioregulator model of tissue-selective transcriptional influence.
- Cardiomyocyte Biology — Investigated for effects on differentiation markers in cardiac cell models.
- Extracellular Matrix — Evaluated in studies of age-associated cardiac tissue composition.
Key Research Applications
- Short peptide bioregulator research
- Cardiac tissue and cardiomyocyte modeling
- Age-associated gene expression studies
Handling & Storage
Lyophilized: Store at –20°C, protect from light and moisture.
Reconstituted: Store at 2–8°C, avoid freeze–thaw cycles.
Research Use Only
This product is supplied strictly for laboratory, research, and development use. Not for human consumption or therapeutic application.
All compounds sold by Tidal are intended exclusively for in-vitro and laboratory research. We do not market our products for human or veterinary use. By placing an order, purchasers acknowledge they are qualified researchers and that materials will be used in compliance with applicable institutional and regulatory standards.
- Purity
- ≥ 99% (HPLC)
- Form
- Lyophilized peptide
- Appearance
- White to off-white powder
- Molecular Weight
- 489.5 Da
- Molecular Formula
- C₁₈H₃₁N₇O₉
- Sequence
- Ala-Glu-Asp-Arg (AEDR)
- Container
- Sterile glass vial
- № 01[The effect of the amino acids and cardiogen on the development of myocard tissue culture from young and old rats] (Adv Gerontol, 2009)Read →
- № 02Interaction of short peptides with FITC-labeled wheat histones and their complexes with deoxyribooligonucleotides (Biochemistry (Mosc), 2013)Read →
- № 03Senescence-Associated Secretory Phenotype of Cardiovascular System Cells and Inflammaging: Perspectives of Peptide Regulation (Cells, 2022)Read →
- № 04Feasibility of Transport of 26 Biologically Active Ultrashort Peptides via LAT and PEPT Family Transporters (Biomolecules, 2023)Read →
Questions
- What sizes does Cardiogen come in?
- Cardiogen comes in 25mg vials (lyophilized peptide), from $59.99. Ordering 3, 5 or 10 vials takes 3%, 6% or 12% off.
- When does Cardiogen ship?
- Orders placed before 2 pm CT on a business day ship the same day from the US. Shipping is free on orders over $100 to the contiguous US. Shipping policy →
- Is Cardiogen for human use?
- No. Cardiogen is sold strictly for in-vitro and laboratory research. It is not for human or veterinary use.
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