MOTS-c is a research peptide used in preclinical laboratory models involving metabolic, mitochondrial, immune, or regenerative pathways.

What is it?

MOTS-c is a mitochondria-derived peptide encoded within the mitochondrial genome and studied in investigational and in vitro research settings for its role in cellular metabolic signaling. Unlike nuclear-encoded peptides, MOTS-c originates from mitochondrial DNA, positioning it as a unique signaling molecule in mitochondrial-to-nuclear communication pathways.

In preclinical and laboratory research models, MOTS-c has been examined for its influence on energy sensing pathways, insulin-related metabolic signaling, and cellular stress adaptation. These characteristics have made it a compound of interest in experimental studies exploring mitochondrial regulation, metabolic flexibility, and adaptive cellular responses to energetic demand.

MECHANISM OF INTEREST

Pathway	Description
Angiogenesis	Observed to influence vascular endothelial pathways.
Tissue Repair	Supports modeling of gastric, tendon, and muscular healing.
Cytoprotection	Evaluated for protective effects in oxidative environments.

KEY RESEARCH APPLICATIONS

- Tissue repair and regeneration research

- Inflammation pathway modeling

- Angiogenesis studies

HANDLING & STORAGE

Lyophilized: Store at –20°C, protect from light and moisture.

Reconstituted: Store at 2–8°C, avoid freeze–thaw cycles.

RESEARCH USE ONLY

This product is supplied strictly for laboratory, research, and development use. Not for human consumption or therapeutic application.