LL-37 is a research peptide used in preclinical laboratory models involving metabolic, mitochondrial, immune, or regenerative pathways.

What is it?

LL-37 is a synthetic form of a human cathelicidin-derived antimicrobial peptide studied in investigational and in vitro research settings. It is a component of the innate immune system and is naturally produced by various cell types, where it participates in first-line defense and immune signaling processes.

In preclinical and laboratory research models, LL-37 has been examined for its role in antimicrobial activity, immune cell signaling, and inflammatory pathway modulation. Beyond direct pathogen interaction, it has also been studied for its involvement in wound-related signaling, angiogenic processes, and epithelial barrier communication, making it a compound of interest in experimental studies focused on host defense and immune response regulation.

MECHANISM OF INTEREST

Pathway	Description
Angiogenesis	Observed to influence vascular endothelial pathways.
Tissue Repair	Supports modeling of gastric, tendon, and muscular healing.
Cytoprotection	Evaluated for protective effects in oxidative environments.

KEY RESEARCH APPLICATIONS

- Tissue repair and regeneration research

- Inflammation pathway modeling

- Angiogenesis studies

HANDLING & STORAGE

Lyophilized: Store at –20°C, protect from light and moisture.

Reconstituted: Store at 2–8°C, avoid freeze–thaw cycles.

RESEARCH USE ONLY

This product is supplied strictly for laboratory, research, and development use. Not for human consumption or therapeutic application.