PE-22-28 is a research peptide used in preclinical laboratory models involving metabolic, mitochondrial, immune, or regenerative pathways.

What is it?

PE-22-28 is a synthetic peptide fragment corresponding to amino acids 22–28 of pancreatic polypeptide, developed for investigational and in vitro research use. It is studied as a selective signaling fragment rather than a full-length metabolic hormone.

In preclinical and laboratory research models, PE-22-28 has been examined for its interaction with neuroendocrine and hypothalamic signaling pathways involved in appetite regulation and energy balance. Its fragment-specific activity has made it a compound of interest in experimental studies exploring satiety signaling, feeding behavior modulation, and central metabolic communication mechanisms.

MECHANISM OF INTEREST

• Angiogenesis: Observed to influence vascular endothelial pathways.
• Tissue Repair: Supports modeling of gastric, tendon, and muscular healing.
• Cytoprotection: Evaluated for protective effects in oxidative environments.

KEY RESEARCH APPLICATIONS

- Tissue repair and regeneration research

- Inflammation pathway modeling

- Angiogenesis studies

SPECIFICATIONS

• Purity: ≥ 98% (HPLC)
• Form: Lyophilized peptide
• Appearance: White to off-white powder
• Molecular Weight: ~1419 Da
• Container: Sterile glass vial

HANDLING & STORAGE

Lyophilized: Store at –20°C, protect from light and moisture.

Reconstituted: Store at 2–8°C, avoid freeze–thaw cycles.

RESEARCH USE ONLY

This product is supplied strictly for laboratory, research, and development use. Not for human consumption or therapeutic application.