Semax is a research peptide used in preclinical laboratory models involving metabolic, mitochondrial, immune, or regenerative pathways.

What is it?

Semax is a synthetic heptapeptide developed for investigational and in vitro research use, structurally derived from a fragment of adrenocorticotropic hormone (ACTH 4–10) with additional modifications to enhance stability. It is primarily studied for its interaction with central nervous system signaling pathways rather than peripheral hormonal activity.

In preclinical and laboratory research models, Semax has been examined for its effects on neurotrophic signaling, synaptic plasticity, and stress-response modulation. These characteristics have made it a compound of interest in experimental studies focused on cognitive function, neuronal resilience, and neuroprotective signaling mechanisms.

Mechanism of Interest

• BDNF Expression — Studied for influence on brain-derived neurotrophic factor levels in neural models.
• Melanocortin Fragment — Investigated as an ACTH(4-10) analog lacking corticotropic activity.
• Monoamine Systems — Examined for effects on dopaminergic and serotonergic signaling in vitro.

Key Research Applications

• Neurotrophic factor research
• Cognitive pathway modeling
• Neuropeptide structure-activity studies

Handling & Storage

Lyophilized: Store at –20°C, protect from light and moisture.

Reconstituted: Store at 2–8°C, avoid freeze–thaw cycles.

Research Use Only

This product is supplied strictly for laboratory, research, and development use. Not for human consumption or therapeutic application.